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What is Proteomics?
Proteomics is the study of all the expressed proteins in an organism (proteome).
This includes the presence or absence of specific proteins and expression levels over time, driven by external stressors, treatments, and/or disease state progression.
Why is Studying Proteomics Important?
Protein expression is directly associated with the potential for disease, its manifestation, and reversion to a normal state.
As part of a multiomics approach along with genomics and transcriptomics, proteomics provides a much more impactful evaluation of an organism at a systems level and hence will lead to quicker and more fruitful discoveries, while helping to identify key clinical and treatment outcomes.
New technologies are being developed to increase sensitivity and throughput beyond Mass Spec, and this is where Olink® and their Proximity Extension Assay (PEA) comes in.
What Can You Do?
Go Beyond Mass Spec
When high throughput and low hands-on time are critical, characterize proteins using Olink methodologies.
Apply the power of NGS sequencing to characterize and quantitate the totality of proteins in your sample.
Initial Screens and More
Access a wide variety of strategic, protein-focused evaluations to suit your needs.
Perform genomic and proteomic interrogation with a small amount of material.
Olink® Proteomics Tools
Actionable, high-throughput human protein profiles specific to cardiometabolic, inflammatory, neurological, and oncological disease states.
We offer full-scale screening of Olink's entire library of 3072 validated protein assays using the Explore 3072-plex format, as well as more targeted Explore 384-, and 1536-plex panels.
Bringing new insights into disease processes, improving disease detection, and enabling faster, better-informed decisions in human protein biomarker research.
We offer Target 48 Cytokine for inflammation-related studies, and the full suite of Target 96 panels for a number of other disease areas — including custom panels.
Olink® Explore 384
The Explore 384-plex panels simultaneously analyzes 384 protein biomarkers using Olink's proprietary PEA technology and Illumina® Sequencing technology.
Choose from any of the Explore 384 Panel options:
- Inflammation / Inflammation II
- Cardiometabolic / Cardiometabolic II
- Neurology / Neurology II
- Oncology / Oncology II
Olink® Explore 1536
Target 48 Cytokine
The Target 48 Cytokine enables the analysis of 45 carefully selected proteins involved in human inflammatory diseases and other inflammatory processes.
Each kit accommodates 40 samples and reports protein expression with both absolute (pg/mL) and relative (NPX) concentration measurements.
Target 96 Panels
The Target 96 protein biomarker panel assays screen 92 different proteins that are focused on a specific disease area and other important biological processes.
Your sample's relative protein expression is determined using PEA to deliver a qPCR readout.
Target 96 Panels:
- Cardiovascular II
- Cardiovascular III
- Cell Regulation
- Immune Response
- Mouse Exploratory
- Neuro Exploratory
- Oncology II
- Oncology III
- Organ Damage
Focus 21 Custom Panels
When you need a very specific set of proteins not covered by Olink's existing panels, the Focus 21 Custom Panels allow you to design your own.
Using Olink's resources and validated PEA technology, you can create an extremely targeted panel of 21 proteins on a qPCR platform for your disease indication of interest.
→ Learn More About Focus Custom Panels
Here are a few important resources with in-depth information about Olink® technologies.
Explore 384 Panel Information
Target 96 Panel Information
Request a Consultation or Quote
Get in touch with your local field team and start designing a project. We’ll help drive your research forward with the right tools for your investigative needs.
Create, Manage and Track Your Project
At this step you'll be able to keep an eye on all the various methods and platforms we’re using to ensure your starting material will produce the most in-depth information possible. It’s easy to get in touch with us if you have a question or concern.
Get Your Data and Analysis Reports
Securely access your raw data and view detailed analyses specific to your scientific question all in one place. Then reach out to our bioinformatics scientists to dig deeper into the results.
Sequential single cell transcriptional and protein marker profiling reveals TIGIT as a marker of CD19 CAR-T cell dysfunction in patients with non-Hodgkin lymphoma
Get the Whole Omics Story, DNA to Protein
Studying each step in the central dogma reveals valuable insights, but DNA-RNA-Protein together tell the whole biological story. Please also consider these other services for your systems biology investigations.