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What is Proteomics?
Proteomics is the study of all the expressed proteins in an organism (proteome).
This includes the presence or absence of specific proteins and expression levels over time, driven by external stressors, treatments, and/or disease state progression.
Why is Studying Proteomics Important?
Protein expression is directly associated with the potential for disease, its manifestation, and reversion to a normal state.
As part of a multiomics approach along with genomics and transcriptomics, proteomics provides a much more impactful evaluation of an organism at a systems level and hence will lead to quicker and more fruitful discoveries, while helping to identify key clinical and treatment outcomes.
New technologies are being developed to increase sensitivity and throughput beyond Mass Spec, and this is where Olink and their Proximity Extension Assay (PEA) comes in.
What Can You Do?
Go Beyond Mass Spec
When high throughput and low hands-on time are critical, characterize proteins using Olink methodologies.
Apply the power of NGS sequencing to characterize and quantitate the totality of proteins in your sample.
Initial Screens and More
Access a wide variety of strategic, protein-focused evaluations to suit your needs.
Perform genomic and proteomic interrogation with a small amount of material.
Olink® Proteomics Tools
Explore 1536 & 3072 Platform
- Best for:
Actionable, high-throughput human protein profiles specific to cardiometabolic, inflammatory, neurological, and oncological disease states
Multiple screening options for measuring the concentration of thousands of human plasma proteins while consuming minute amounts of sample using PEA, with an Illumina sequencing normalized protein expression (NPX) output
→ Learn More About the Explore Platform
Target 96 Panels
- Best for:
Determining your sample's protein relative expression
Various systematically directed protein panels using PEA to deliver a qPCR readout
→ Learn More About Target Panels
Target 48 Cytokine
- Best for:
Evaluating human cytokine signaling and inflammation pathways
A very focused, 48-protein panel delivers protein expression as absolute quantification through qPCR
→ Learn More About Target 48 Cytokine
Focus 21 Custom Panels
- Best for:
When you need a very specific set of proteins not covered by existing panels and you want to design your own for your disease indication of interest
→ Learn More About Focus Custom Panels
Request a Consultation or Quote
Get in touch with your local field team and start designing a project. We’ll help drive your research forward with the right tools for your investigative needs.
Create, Manage and Track Your Project
At this step you'll be able to keep an eye on all the various methods and platforms we’re using to ensure your starting material will produce the most in-depth information possible. It’s easy to get in touch with us if you have a question or concern.
Get Your Data and Analysis Reports
Securely access your raw data and view detailed analyses specific to your scientific question all in one place. Then reach out to our bioinformatics scientists to dig deeper into the results.
Sequential single cell transcriptional and protein marker profiling reveals TIGIT as a marker of CD19 CAR-T cell dysfunction in patients with non-Hodgkin lymphoma
Get the Whole Omics Story, DNA to Protein
Studying each step in the central dogma reveals valuable insights, but DNA-RNA-Protein together tell the whole biological story. Please also consider these other services for your systems biology investigations.