Bioinformatic Services | Psomagen, Inc.

What Is Bioinformatics?

Bioinformatics software tools and pipelines help scientists analyze data. After NGS is complete, a demultiplexing step associates each read with its sample of origin based on its unique DNA barcode. The raw data file generated is a bcl file (binary base call) or fastq file (text-based). Through data mining, each sample’s sequences are then aligned to known reference and annotation information to provide in-depth analysis to provide phenotype, variant calls, and gene expression among other in-depth analysis.

Why Is Bioinformatics Important?

Sequencing generates daunting masses of data. Analyzing it manually is not a reasonable option.

Fortunately, a variety of bioinformatics tools can be applied for fast interpretation, to enhance our understanding of biology, improve disease diagnostics, and/or aid in therapeutic development.

Bioinformatics Tools

Genomics Analysis

Actionable, high-throughput human protein profiles specific to cardiometabolic, inflammatory, neurological, and oncological disease states.

Single Nucleotide Variants (SNV)
Insertions and Deletions (Indel)
Copy Number Variants (CNV)
Structural Variants (SV)
Somatic Mutation Identification
Annotated Reporting
Family Trio Analysis
Pathogenicity Scoring
Phenotype Relationship

Epigenomics Analysis

Actionable, high-throughput human protein profiles specific to cardiometabolic, inflammatory, neurological, and oncological disease states.

Methylation Profiling
Functional Location Mapping
Differentially Methylated CpGs
Annotated Peak Calling
Peak Visualization
Motif Discovery
Small RNA Expression Profile
Categories of Small RNA

Transcriptomics Analysis

Actionable, high-throughput human protein profiles specific to cardiometabolic, inflammatory, neurological, and oncological disease states.

Gene Expression
Alternative Splicing
Novel Transcript Identification
Isoform Identification
Variant Annotation
Single Nucleotide Variants (SNV)
Fusion Gene Identification
Novel Alternative Transcript Identification
Differential Gene Expression (DEG)
10X scRNA Cell Ranger
10X scRNA Aggregation & Seurat Analysis
10X scRNA Trajectory Analysis

Proteomics Analysis

Actionable, high-throughput human protein profiles specific to cardiometabolic, inflammatory, neurological, and oncological disease states.

Normalized Protein Expression (NPX)
Absolute Protein Quantitation (available for Target 48, Flex, and Focus)
Statistical Analyses
Data Visualization

Download Sample Reports:

Olink Target 48
Olink Target 96
Olink Explore HT
Olink Explore 3072

Single-Cell Analysis

Analysis Grade	Species	Tier	cellranger mkfastq output	cellranger count output	cellranger aggr output	Seurat I	Seurat II
Basic	Human/ mouse	I	Yes	No	No	No	No
		IIA	Yes	Yes	No	No	No
		IIB	Yes	Yes	Yes	No	No
Advanced	Human/ mouse	III	Yes	Yes	Optional	Yes	No
Premium	Human/ mouse/ other*	IV	Yes	Yes	Optional	Yes	Yes

*Any species with a completed reference genome available.

Download a Sample Report:

Single-cell RNA sequencing

Spatial Biology Analysis

Combine data from multiple samples and multiple platforms into one comprehensive analysis with Aspect Analytics. Want to include M/S-based proteomics, metabolomics, or lipidomics? Validated pipelines are ready for your project.

We're Ready for Your Order!

Here's what to expect in your project's life cycle. If you have a question during sequencing, it's easy to get in touch!

01

Request a Consultation

Create an account through our client portal and get in touch with your local field team to start designing a project.

We’ll help drive your research forward with the right tools for your research needs.

02

Place an Order

After finalizing the scope of work, the official quote will be issued for signing. Then, your sales representative will send specific shipping instructions.

Once all the samples and necessary documents are ready, we can start your project. Need more analysis? Reach out to our bioinformatics experts to dig deeper.

03

QC and Data Delivery

All Psomagen sequencing projects come with a built-in QC step to ensure you get the information you need. An account manager will update you on your project's progress in a timely manner.

You can also see some project information and securely view all valid reports on the client portal site.

Bioinformatics in Action

More Customer Publications

Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders

End-to-End Multiomics Services

Harness Psomagen’s full portfolio of services to power your combined genomics, transcriptomics, and proteomics investigations. Then employ our formidable bioinformatics capabilities to unlock a wealth of knowledge and enable discoveries.

Genomics

The most comprehensive way to investigate an entire genome.Get the whole story, including exons, introns, and untranslated regions (UTR).

Epigenomics

More ways to elucidate gene expression. Find solutions such as ATAC and ChIP-seq to further investigate how protein and nucleic acid interact.

Transcriptomics

A more complete picture of various disease states. Take a closer look at both coding and non-coding RNA — mRNA, smRNA, lncRNA, and more — with a variety of sequencing strategies.

Proteomics

A novel way to predict and understand human illness. Go beyond the nucleic acid map and identify and quantify the protein biomarkers that are the hallmarks of the disease.

Omics Research

Bioinformatics

What Is Bioinformatics?

Bioinformatics Tools

Genomics Analysis

Epigenomics Analysis

Transcriptomics Analysis

Proteomics Analysis

Single-Cell Analysis

Spatial Biology Analysis

We're Ready for Your Order!

01

Request a Consultation

02

Place an Order

03

QC and Data Delivery

Bioinformatics in Action

Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders

End-to-End Multiomics Services

Genomics

Epigenomics

Transcriptomics

Proteomics

PSO Clear!

Can’t see past mounds of data? Make your data actionable and gain clarity from our experts.

Subscribe to Our Newsletter