BioSkryb Genomics Single-Cell

How It Works

One-cell-per-well method sorts each cell into a separate well for unique barcoding. Provides more efficient RNA capture within a cell, reducing the need for high cell numbers. Compared to droplet-based technologies, this approach yields roughly 3x more data per single cell.

Primary-Template Directed Amplification (PTA) Technology

PTA improves on existing DNA amplification technologies by generating shorter amplicons and redirecting primers back to the primary DNA template. This decreases the risk of errors common in multiple displacement amplification. PTA genome coverage is more uniform and accurate.

Psomagen currently offers sequencing for pre-made BioSkryb libraries. If you are looking for the complete workflow, please inquire.

Bioskryb options at psomagen

ResolveOME

The ResolveOME Whole Genome and Transcriptome Single-Cell Core Kit makes it possible to analyze the genome and transcriptome from the same single-cell sample. With ResolveOME, analyze:

Cell type diversity
Mechanistic alterations in the genome
Phenotypic effect on the transcriptome
Inferred impact of protein sequence alterations

ResolveDNA

Offering industry-leading genomic amplification, the ResolveDNA Whole Genome Amplification Kit tackles a historic problem of low coverage uniformity with over 95% genome coverage in single cells. See the difference with:

Complete genomic coverage
Low allelic dropout
96% SNV sensitivity

More Single-Cell at Psomagen

Our labs are always adding more technologies and capabilities to our Spatial Biology & Single-Cell Center of Excellence. This means you'll be able to find the platform that suits your project. Take a look at other options below.

Fluent Biosciences

Now an Illumina company, Fluent Biosciences offers high-throughput, instrument free emulsion for multiplexing many samples in a single reaction.

10x Genomics

We're a 10x Certified Service Provider for 3' and 5' Gene Expression, ATAC, CRISPR screening, immune profiling, and more.

PacBio Long-Read Single Cell

Library preparation for full length, long-read cDNA generated by the 10x Genomics Kinnex single cell kit, which creates a PacBio compatible, SMRTbell library. Enables isoform and fusion detection without the need for assembly.

Scale Biosciences

QuantumScale single-cell RNA offers flexibility and efficiency without sacrificing high sensitivity and quality. Capture and fix up to 4 million cells, ideal for studies with multiple timepoints.

Parse Biosciences

A unique, plate based approach for highly multiplexed cell capture, scalable to your project's needs.

Omics Research // SINGLE-CELL SEQUENCING

BioSkryb Genomics