What Is Transcriptomics?
Transcriptomics is the study of RNA and its expression through sequencing, to analyze the impact of gene expression on the biology of an organism.
These analyses may include the entire transcriptome, messenger RNA, small RNAs, and non-coding RNA.
What Is RNA Sequencing?
RNA sequencing is one of the main ways to conduct transcriptomic research (the study of RNA and its expression). With transcriptomics, researchers can sequence RNA to analyze the impact of gene expression on the biology of an organism.
These analyses may include the entire transcriptome, messenger RNA, small RNAs, and non-coding RNA.
Why Is RNA-Seq Important?
RNA-sequencing provides a real-time snapshot of what messages are available to drive translation to protein expression. In contrast to whole exome sequencing (WES), RNA-seq enables the researcher to quantify the gene expression at that specific time the sample was collected. The impact of drug target outcomes on regulation of gene expression can be assessed at the transcription level.
In addition, drug candidates that incorporate specialized RNA molecular technologies such as siRNA, shRNA, and CRISPR must be assessed for targeted efficacy and to rule out off-target effects.
What Can You Do?
See Non-Coding RNA Impact
Use total RNA sequencing for the broadest scope of information.
Detect Splice Variants
Determine how alternative splicing is affecting transcript expression.
Regulate miRNA Expression
Use small RNA sequencing to help define which micro RNA (miRNA) species are present and impacting overall expression.
Disease Research
Evaluate RNA-based therapies and investigate disease-related RNA changes
Transcriptomics Methods
Our available technologies, plus common applications for each type of transcriptomics research.
RNA Sequencing
- Discover, profile, and quantify RNA transcription to understand how genes are expressed in an entire organism, specific tissue / structure, or a single cell.
- Gain insight into the biology of a cell and how cellular changes may relate to disease.
- Understand the impact of gene expression, alternative splicing events, gene fusions, and allele-specific expression of rare and novel messages.
- Evaluate RNA-based therapies and disease-related RNA changes.
Viral RNA Sequencing
- Identify and classify viral variants of concern, including COVID-19. Using nasal swabs and other sample types, you can identify common and novel variants.
- Avoid dropouts (non-amplification due to mutations in primer binding regions) with our IDT® xGen™ SARS-CoV-2 Expanded Amplicon Panel, raising confidence that it will identify emerging variants.
Iso-Seq
- Use PacBio Single Molecule, Real-Time (SMRT) technology to sequence the full length cDNA.
- The Sequel IIe platform can be used to perform sequencing on your RNA samples, capturing many isoforms that may not be detected by standard RNA-Seq.
RNA Sequencing Tools
Save on RNA Projects
We frequently offer deals on miRNA, mRNA, and Total RNA sequencing technologies. Check in often for updated promotions.
Why Our Clients Choose Psomagen
Superior Data Quality
Exceeds manufacturer benchmarks
Fast Turnaround
Starting at one week for sequencing projects
US-Based Processing
Sequencing and customer support in Rockville, MD
Ph.D. Level Support
Expert assistance every step of the way, with real-time project updates through our online system
Automated Workflows
Increase scalability and improve reproducibility
CLIA-Certified, CAP-Accredited Labs
Clinical research options available (inquire for more information)
Complete Sequencing Solutions
From extraction to data analysis, with many sample types accepted
Quotes From Our Clients
I chose Psomagen because of the price and US-based labs. We've used Psomagen before and were very satisfied. The people were responsive and helpful and the work done was very good.
Professor
University Research Laboratory
I chose Psomagen because of the price and US-based labs. We've used Psomagen before and were very satisfied. The people were responsive and helpful and the work done was very good.
Professor
University Research Laboratory
I chose Psomagen because of the price and US-based labs. We've used Psomagen before and were very satisfied. The people were responsive and helpful and the work done was very good.
Professor
University Research Laboratory
Transcriptomics in Action
End-to-End PSOlutions
Unlock a wealth of knowledge and enable discoveries with Psomagen’s full portfolio of services and powerful bioinformatic capabilities that complement your transcriptomic efforts.
