Transcriptomics

Sequence RNA to understand how genes are being expressed in an organism or a single cell.

What is Transcriptomics?

Transcriptomics is the study of RNA and its expression through sequencing, to analyze the impact of gene expression on the biology of an organism.

These analyses may include the entire transcriptome, messenger RNA, small RNAs, and non-coding RNA.

Why Is Studying Transcriptomics Important?

Transcriptomics provides a real-time snapshot into what messages are available to drive translation to protein expression.

In addition, drug candidates that incorporate specialized RNA molecular technologies such as siRNA, shRNA, and CRISPR must be assessed for targeted efficacy and to rule out off-target effects.

What Can You Do?

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See Non-Coding RNA Impact

Use total RNA sequencing for the broadest scope of information.

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Detect Splice Variants

Determine how alternative splicing is affecting transcript expression.

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Regulate miRNA Expression

Use small RNA sequencing to help define which micro RNA (miRNA) species are present and impacting overall expression.

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Offer Precision Medicine

Introduce new ways to prevent, diagnose, and treat disease on a personalized level.

Transcriptomics Methods

RNA Sequencing

Best for:
Discovering, profiling, and quantifying RNA transcription to understand how genes are expressed in an organism or a single cell
Benefits:
Insight into the biology of a cell and how changes — gene expression, alternative splicing events, gene fusions, and allele-specific expression of rare and novel messages — may relate to disease. Evaluation of RNA-based therapies and disease-related RNA changes.

Single-Cell Sequencing

Best for:
Gene expression research of individual cells in heterogeneous tissues or cell populations as well as precision genomics discovery and development
Benefits:
Certified Service Provider (CSP) for multiple single-cell sequencing technologies from 10x Genomics^®

Microarray Analysis

Best for:
Large-scale, high-throughput genomic analyses
Benefits:
Understand gene expression and quantify disease-related mutations for cost-effective development of better disease detection methods and treatment efficacy monitoring

SARS-CoV-2 Variant Surveillance

Best for: Identifying and classifying all variants of concern, including Omicron
Benefits: Our IDT^® xGen™ SARS-CoV-2 Expanded Amplicon Panel is designed to avoid dropouts (non-amplification due to mutations in primer binding regions), raising confidence that it will identify emerging variants.

Quotes From Our Clients

"We had a large project that needed 150 bp paired end sequencing. Psomagen had the best price (and we surveyed a lot of suppliers!) and prompt delivery. Absolutely no problems, every step of the way went smoothly."

Ravi Sachidanandam, Ph.D.

Mount Sinai School of Medicine

"It's worth buying from Psomagen."

Ayesha Liaqat, Ph.D.

UMCES-Imet

"Great service, high-quality reads, and fast turnaround time."

Christophe Cataisson, Ph.D.

NCI

End-to-End PSOlutions

Unlock a wealth of knowledge and enable discoveries with Psomagen’s full portfolio of services and powerful bioinformatic capabilities that complement your transcriptomic efforts.

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Genomics

The most comprehensive way to investigate an entire genome. Get the whole genetic story or focus on the role of exons, introns, and untranslated regions using cutting-edge tools and technologies.

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Metagenomics

A new understanding of the world’s biosphere. Discover the biological diversity in environmental and microbial samples and their evolution and function.

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Epigenomics

More ways to elucidate gene expression. Find solutions such as ATAC and ChIP-seq to further investigate how protein and nucleic acid interact.

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Proteomics

A novel way to predict and understand human illness. Go beyond the nucleic acid map and identify and quantify the protein biomarkers that are the hallmarks of disease.