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Omics Research

Transcriptomics

Sequence RNA to understand how genes are being expressed in an organism or a single cell.

Let’s Talk About Transcriptomics

What is Transcriptomics?

 

Transcriptomics is the study of RNA and its expression through sequencing, to analyze the impact of gene expression on the biology of an organism. 

 

These analyses may include the entire transcriptome, messenger RNA, small RNAs, and non-coding RNA. 

 

Why Is Studying Transcriptomics Important?

 

Transcriptomics provides a real-time snapshot into what messages are available to drive translation to protein expression. 

 

In addition, drug candidates that incorporate specialized RNA molecular technologies such as siRNA, shRNA, and CRISPR must be assessed for targeted efficacy and to rule out off-target effects.

What Can You Do?

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See Non-Coding RNA Impact

Use total RNA sequencing for the broadest scope of information.

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Detect Splice Variants

Determine how alternative splicing is affecting transcript expression.

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Regulate miRNA Expression

Use small RNA sequencing to help define which micro RNA (miRNA) species are present and impacting overall expression.

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Offer Precision Medicine

Introduce new ways to prevent, diagnose, and treat disease on a personalized level.

Transcriptomics Methods

RNA Sequencing
  • Best for:
    Discovering, profiling, and quantifying RNA transcription to understand how genes are expressed in an organism or a single cell

  • Benefits:
    Insight into the biology of a cell and how changes — gene expression, alternative splicing events, gene fusions, and allele-specific expression of rare and novel messages — may relate to disease. Evaluation of RNA-based therapies and disease-related RNA changes. 

    More on RNA Seq
Single-Cell Sequencing
  • Best for:
    Gene expression research of individual cells in heterogeneous tissues or cell populations as well as precision genomics discovery and development

  • Benefits:
    Certified Service Provider (CSP) for multiple single-cell sequencing technologies from 10x Genomics® 

    More on Single-Cell Sequencing
Microarray Analysis
  • Best for:
    Large-scale, high-throughput genomic analyses

  • Benefits:
    Understand gene expression and quantify disease-related mutations for cost-effective development of better disease detection methods and treatment efficacy monitoring 

    More on Microarrays
SARS-CoV-2 Variant Surveillance
  • Best for: Identifying and classifying all variants of concern, including Omicron 

  • Benefits: Our IDT® xGen™ SARS-CoV-2 Expanded Amplicon Panel is designed to avoid dropouts (non-amplification due to mutations in primer binding regions), raising confidence that it will identify emerging variants.

    More on SARS C0V-2 Surveillance

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PSO Prepared!

From genome-wide analysis to single-cell specifics, we make it easy to embed transcriptomics in your discovery project planning.

Plan Your Project

End-to-End PSOlutions

Unlock a wealth of knowledge and enable discoveries with Psomagen’s full portfolio of services and powerful bioinformatic capabilities that complement your transcriptomic efforts.

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Genomics
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Proteomics
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